Novo Nordisk

Novo Nordisk Information

Headquarters: Bagsværd, Denmark

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Therapeutic Areas

  • Diabetes
  • Immunology
  • General Medicine
  • Obesity and Weight Management

Pipeline Overview

Key pipeline highlights include:

  • CagriSema — Novo Nordisk’s next-generation obesity therapy combining cagrilintide (amylin analog) and GLP-1 semaglutide, with Phase 3 REDEFINE-1 results showing weight loss of up to 22.7% of body weight over 68 weeks. The company aims to file in early 2026 for a potential approval.
  • Wegovy Pill (oral semaglutide 25 mg) — The first and only once-daily oral GLP-1 medicine approved for chronic weight management, delivering 16.6% weight loss if all study participants adhered to treatment on par with injectable Wegovy (semaglutide 2.4 mg).
  • Zenagamtide — A unimolecular, long-acting GLP-1 and amylin receptor agonist available in both subcutaneous and oral formulations. Phase 2 results showed HbA1c reductions of up to 1.8% subcutaneously, with 89% of participants reaching target levels below 7%. Phase 3 for weight management is underway in the first quarter of 2026.
  • Ziltivekimab — A monoclonal antibody targeting IL-6 activity, being studied for cardiovascular disease with Phase 3 readouts expected in 2026–2027.
  • Mim8 — A next-generation FVIIIa-mimetic bispecific antibody for hemophilia, with Phase 3 dosing initiated.
  • Akero Therapeutics (EFX) — In October 2025, Novo Nordisk acquired Akero Therapeutics for $5.2 billion, a clinical-stage company focusing on the treatment of metabolic dysfunction-associated steatohepatitis (MASH).

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