Sanofi Ends Amlitelimab Atopic Dermatitis Development, Will Not Seek Global Regulatory Approval

sanofi news

Sanofi has discontinued amlitelimab in moderate-to-severe atopic dermatitis and will not pursue global regulatory submissions, citing ESTUARY phase 3 data that did not show a meaningful edge over standard of care. Full-year 2026 guidance is unaffected.

Danaher Corporation Q2 2026 Financial Results; Strategic Capital Allocation, and Market Valuation Dynamics

Danaher Business System Updates

Danaher Corporation (NYSE: DHR) reported strong second-quarter 2026 financial results, generating revenue of $6.265 billion (+5.5% YoY) and non-GAAP adjusted diluted earnings per share (EPS) of $1.94 (+8.0% YoY), with both key metrics outperforming Wall Street consensus estimates. Non-GAAP core sales grew 3.0% overall and 4.5% when excluding post-pandemic respiratory testing normalizations, driven by a rebound across Life Sciences workflows and continued adoption of clinical diagnostics menus.

Novartis Q2 2026 Results: Kisqali, Kesimpta, and Pluvicto Drive Return to Sales Growth

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Novartis Q2 2026 results show a return to sales growth, with net sales up 3% to $14.4 billion on strong demand for Kisqali, Kesimpta, Scemblix, and Pluvicto, as the company reaffirmed its full-year 2026 guidance and advanced key pipeline programs including Fabhalta and Rhapsido.

Novo Nordisk Eli Lilly Lawsuit: Novo Nordisk Sues Eli Lilly Over Misleading Wegovy, Ozempic Ad Comparisons

Novo Nordisk Information

Novo Nordisk has filed a federal lawsuit accusing Eli Lilly of running misleading Zepbound and Mounjaro ads that compare outdated, lower doses of Wegovy and Ozempic — omitting newer, FDA-approved higher-strength options.

Novartis Fabhalta Iptacopan FDA Approval Becomes First Complement Inhibitor to Slow Kidney Decline in Primary IgAN

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The FDA has granted traditional approval to Novartis’ Fabhalta (iptacopan) — the first complement inhibitor shown to significantly slow kidney function decline in adults with primary IgA nephropathy. Phase III APPLAUSE-IgAN data showed a 48% slower eGFR decline versus placebo over two years.

LIPFENDRA FDA Approval: Merck’s Enlicitide Becomes First Oral PCSK9 Inhibitor to Lower LDL-C

Merck MSD

The LIPFENDRA FDA approval makes Merck’s enlicitide the first once-daily oral PCSK9 inhibitor cleared to lower LDL-C in adults with hypercholesterolemia, including HeFH. Phase 3 CORALreef data showed placebo-adjusted LDL-C reductions of 56–59% at 24 weeks.

Merck’s Erbitux BRAF V600E mCRC Regimen Gets EU Approval for First-Line Treatment

Merck KGaA News

The European Commission has approved Merck’s Erbitux BRAF V600E mCRC combination regimen cetuximab plus encorafenib and FOLFOX as first-line therapy for metastatic colorectal cancer with the BRAF V600E mutation, based on Phase 3 BREAKWATER data showing a 51% reduction in risk of death versus standard chemotherapy.