A novel method predicts how a certain DNA sequence will organize itself in the cell nucleus in a matter of minutes as opposed to days.
Data from this 28-country multi-institutional effort helped the Food and Drug Administration (FDA) approve this combination more quickly in December 2024, giving patients with BRAF V600E-mutant mCRC a new and effective first-line treatment choice.
The combination immunotherapy affected distant metastases in addition to the treated tumors. It increased the sensitivity of melanomas to checkpoint inhibitors and decreased the creation of new metastases, hence reducing malignant relapses.
Humans and pigs can contract the virus, which fruit bats carry. Additionally, it can spread directly from person to person by coughing droplets and contaminated food.
HIV-1, like other viruses, lacks the equipment to generate its own proteins and must rely on the host cell to translate its genetic instructions.
The codon chart is an important tool in the fields of molecular biology and genetics, allowing the translation of the genetic code into specific amino acids, creating the basis for protein synthesis in all life forms. The interpretation of the codon chart implies comprehension of the structure of genetic material […]
Glycolysis is one of the most fundamental metabolic pathways found in nearly all living organisms. In glycolysis, a simple sugar (glucose) is broken down to produce energy in the form of ATP (adenosine triphosphate). This process takes place in the cell cytoplasm and is the first step in both aerobic […]
What is Micro RNA or miRNA? Micro RNAs belong to small non-coding RNA molecules involved in the regulation of gene expression. These short RNA sequences, typically of around 20-25 nucleotides, have emerged as important regulators of biological processes, ranging from cell development to the development of disease, with much importance […]
Sanger sequencing, also known as the dideoxy chain-termination method, is one of the cornerstone techniques for determining the exact nucleotide sequence of DNA. Introduced by Frederick Sanger and co-workers in 1977, it has been an important tool for genetic research, especially for determining entire genomes, such as in the Human […]
Monoclonal antibodies revolutionized medicine by introducing a range of targeted therapies against malignant diseases, autoimmune disorders, infectious diseases, and many others. They are engineered from a single clone of cells to bind to antigens with very high precision. This article presents the underlying science behind monoclonal antibodies, including their applications, […]
