Here the investigators infected mice with SARS-CoV-2 and sequenced the genomes of viruses replicating in the brain versus the lung. In the lung, spike protein had a very close structure to the infecting virus.
Disease Biology
New findings out of Emory University are shaking theories of the origin of Alzheimer’s the leading cause of dementia among older adults worldwide.
The first study in the world, conducted recently at the University of Eastern Finland, demonstrates that even in those with a high hereditary risk, type 2 diabetes may be prevented with a balanced diet and frequent exercise. Put another way, regardless of hereditary risk, everyone gains from changing their lifestyle. […]
Recently, Japanese researchers discovered endolysin, an enzyme generated from bacteriophages that may attack Enterococcus faecalis biofilms. Their results provide promise for customized allo-HCT therapies.
The study investigated if cancer status differed according to individuals’ RAS genetic variations.
One of the novel synthesis’s key features is a bioinspired photooxygenation-allylic hydroperoxide rearrangement sequence that makes it easier to add functional groups in the synthesis’s final stages.
A diagnosis of the underlying pathology is required for the development of therapies and for stratifying patients according to their disease.
The researchers discovered that a statin called pitavastatin efficiently decreases IL-33 expression by preventing the activation of the TBK1-IRF3 signalling pathway.
When the medication was given to mice whose tumors had been surgically removed, similar results were also shown.
The drug is special, say the researchers, since it specifically targets the beta cells in the pancreas that produce insulin and is made to protect those cells against the immune system attacks.
