Clinical Trials Observed Cardiovascular Death and Worsening Heart Failure Reduced by Finerenone
The rates of heart failure events and cardiovascular death were lower in the finerenone group compared with the placebo group.
The rates of heart failure events and cardiovascular death were lower in the finerenone group compared with the placebo group.
This new research, published in Alzheimer’s & Dementia, suggested that the cognitive impairments of COVID-19 presented similar fundamental changes within the brain to those showing evidence of dementia.
A landmark 2018 study, Garvan scientists were the first in the world to directly observe i-motifs inside living human cells using a new antibody tool they had developed, that was able specifically to bind to them.
The researchers collected several thousand cells in each brain from a region of the brain that is affected by Alzheimer’s and ageing.
Here the investigators infected mice with SARS-CoV-2 and sequenced the genomes of viruses replicating in the brain versus the lung. In the lung, spike protein had a very close structure to the infecting virus.
Mitochondria live in all our cells, but unlike other organelles, mitochondria sport their own DNA—a small, circular strand with about three dozen genes.
The researchers focused on mouse retinal ganglion cells in the study, which project from the retina to the superior colliculus a part of the brain where they synapse onto downstream target neurons.
Results showed that the deletion of a protein, OpgH, in a model bacterium, Caulobacter crescentus, sets off an event cascade that ultimately splits apart the protective, bubble-like cell envelope, eventually killing the cell.
One of the curious features of the thymus, however, is that it serves as the very first organ in our body to become small with age.
New findings out of Emory University are shaking theories of the origin of Alzheimer’s the leading cause of dementia among older adults worldwide.