AbbVie and Genmab Announce Epcoritamab R-CHOP Cuts Progression Risk by 51% in Newly Diagnosed DLBCL in Phase 3 EPCORE DLBCL-2 Trial

AbbVie News

AbbVie and Genmab report that Epcoritamab R-CHOP reduced the risk of progression or death by 51% versus R-CHOP alone in newly diagnosed diffuse large B-cell lymphoma, in the Phase 3 EPCORE DLBCL-2 trial. The combination remains investigational.

AbbVie and Genmab Announce Positive Phase 3 Results for Epcoritamab in Relapsed/Refractory DLBCL

AbbVie

AbbVie and Genmab have announced significant topline results from the pivotal Phase 3 EPCORE® DLBCL-1 trial. The study marks a clinical milestone as the first Phase 3 trial to demonstrate a statistically significant improvement in progression-free survival (PFS) for a CD3xCD20 bispecific antibody monotherapy in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL).