Swiss healthcare giant Roche is advancing prasinezumab, a potential first-in-class anti-alpha-synuclein antibody for early Parkinson’s disease, into Phase III trials. This decision follows encouraging data from the Phase IIb PADOVA study and its long-term follow-up, suggesting the drug offers clinical benefits.

Researchers have discovered that phosphorylated α-synuclein, a protein linked to several neurodegenerative illnesses, including Parkinson’s disease and Lewy body dementia, is also engaged in the regular processes of neuronal communication in a healthy brain. The National Institute of Neurological Disorders and Stroke (NINDS), a division of the National Institutes of Health, provided […]