Alzheimer’s disease is caused by a cellular population in the brain
The researchers collected several thousand cells in each brain from a region of the brain that is affected by Alzheimer’s and ageing.
The researchers collected several thousand cells in each brain from a region of the brain that is affected by Alzheimer’s and ageing.
Here the investigators infected mice with SARS-CoV-2 and sequenced the genomes of viruses replicating in the brain versus the lung. In the lung, spike protein had a very close structure to the infecting virus.
Mitochondria live in all our cells, but unlike other organelles, mitochondria sport their own DNA—a small, circular strand with about three dozen genes.
Naturally, the code depends upon the assistance of massive proteins called transcription factors, which determine which genes in one’s genome are turned on or off.
The researchers focused on mouse retinal ganglion cells in the study, which project from the retina to the superior colliculus a part of the brain where they synapse onto downstream target neurons.
Results showed that the deletion of a protein, OpgH, in a model bacterium, Caulobacter crescentus, sets off an event cascade that ultimately splits apart the protective, bubble-like cell envelope, eventually killing the cell.
One of the curious features of the thymus, however, is that it serves as the very first organ in our body to become small with age.
New findings out of Emory University are shaking theories of the origin of Alzheimer’s the leading cause of dementia among older adults worldwide.
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