The Human Genome Project was a major scientific study in the history of life-sciences. This project was lead to many biological discoveries which can aid the future research and developments. The aim of the project was to study all the DNA or Genomes of the selected set of organisms. This project was started in 1990 and was completed in 2003. It is the largest collaborated biological project. At the end of the project in 2003, almost 90% of the human genome was analyzed. This work plays a major role in the biomedical research as it provided source for major key researches. DNA sequencing was the principle work done for the analysis of the genomes of the humans.
DNA Sequencing
DNA sequencing is the process in which the bases in the DNA are determined exactly in the order. It used a specific DNA sequencing method called as the Sanger DNA Sequencing as the principle DNA sequencing procedure.
Major Institutes Involved
- MIT Center for Genome Research
- The Wellcome Trust Sanger Institute
- Washington University
- RIKEN Genomic Sciences Center
- French Alternative Energies and Atomic Energies Commission
- Genomic Therapeutics Corporation
- Beijing Genomic Institute
- United States Department of Energy
- Max Planck Society
Specimen Collection
The sample was collected not from a single person, as it had the name Human Genome Project, it had collected blood sample from random multiple persons. The name and other details about the donors were kept unrevealed. Most commonly the samples were collected from the volunteers pf this project with their consent. Almost major percentage of the human genome sequence generated in this project was from buffalo.
7 Goals of HGP
The major 7 goals of the Human Genome Project was
- Sequencing the entire human genome
- Optimization of the data for analysis
- Development of a database for the storage of the data
- Identification of the total human genome
- To understand the legal, ethical and social issues related to the project
Impact of the Human Genome Project
The data collected form the Human Genome Project was used for the research and development in various areas of interest. Commonly data used in biomedical research for the advancement of the genetic disease identification and further research.The main objective of the project was the development of the database contain the whole genome data which lead to the advancement of the Bioinformatics. International HapMap Project was associated with this which was a collaboration aimed for the identification of human genetic disease variation through the haploid gentotype map of the human genome. HGP also advances other fields beyond Biomedical research such as forensic science and anthropology. In the field of forensics it is used for the identification of the culprits on the basis pf evidences like fingerprint, blood stain, semen, etc. This also made a preventiveness against future crimes.
In anthropology it is used to study about the evolution of Homo sapiens, their ancient life, migration, and survival. This made to study and identify the relationship of different populations.
Graduated from the University of Kerala with B.Sc. Botany and Biotechnology. M.Sc. Biotechnology from the University of Kerala. Attended certificate course in Artificial Intelligence for Everyone from Deeplearning.AI, Influenza Prevention and Control from World Health Organization. Attended workshops related to Bioinformatics at the University of Kerala. 3 years of experience in website management. Experience in WordPress, Blogger, Google Analytics, and Google Search Console.
Related Articles
Achuth B S
Graduated from the University of Kerala with B.Sc. Botany and Biotechnology. M.Sc. Biotechnology from the University of Kerala. Attended certificate course in Artificial Intelligence for Everyone from Deeplearning.AI, Influenza Prevention and Control from World Health Organization. Attended workshops related to Bioinformatics at the University of Kerala. 3 years of experience in website management. Experience in WordPress, Blogger, Google Analytics, and Google Search Console.
Sun Apr 23 , 2023
Deoxyribonucleic Acid, or DNA for short, is often referred to as the blueprint of life. It is the genetic material that makes up all living organisms, from single-celled bacteria to complex multicellular animals like humans. DNA contains the instructions that determine an organism’s traits, such as eye color, height, and […]
