An approval which can transform the treatment technology for β-thalassemia and sickle-cell disease
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Intratumoral therapy, in which cancer drugs are injected directly into tumors
A University of Alberta team has developed a new step to improve the process for creating insulin-producing pancreatic cells from a patient’s own stem cells, bringing the prospect of injection-free treatment closer for people with diabetes.
Researchers discovered that after previously being exposed to mustard oil, those with so-called Neanderthal variations in the sensory neuron-related gene SCN9A are more susceptible to pain from skin pricking. Three mutations in the SCN9A gene, referred to as M932L, V991L, and D1908G, have been found in sequenced Neanderthal genomes and there have been reports of increased pain sensitivity in people who possess all three variants. The precise sensory responses impacted by these variations were unknown, though, until this study.
Washington State University has developed a new technology for the development of cells using a bioreactor for cancer therapy. this technique develops cancer-detecting white blood cells (WBC) which supports immunotherapy.
Researchers at Washington State University have created a bioreactor the size of a minifridge that can produce T cells at 95% of their maximal development rate, which is around 30% quicker than what is possible with existing technology. They developed it using T cells from cattle. They expect it will function similarly on human cells.
Researchers at the University of Cambridge have proven that a simple blood test is enough for the diagnosis of bipolar disorder. They used a combination of online psychiatric assessments and blood tests to diagnose patients with bipolar disorder.
The initial analysis took place within weeks using X-ray diffraction, Scanning Electron Microscopy (SEM), and infrared measurements. These produced the 3D computer model of the particles which gave an idea about internal and external structure. This analysis gives the initial data about carbon content and water.
A recent research study led by Karin Schelch and Michael Grusch from MedUni Vienna identified the oncoprotein YB-1 as an attractive therapeutic target in PM and demonstrates that indirect targeting of YB-1 is a promising approach to enhance sensitivity to chemo- and radiotherapy.
With the advancement of stem cell technology and 3D printing, researchers at the University of Oxford developed a 3D printing method for the purpose of repairing brain injuries. It was initially tested in mouse brain fragments, to this the implant was attached. These implants then got integrated with the mouse brain fragments. This newly developed technology can be used for curing lethal brain injuries.
The 2023 Nobel Prize for Physiology or Medicine was jointly awarded to Hungarian and U.S. scientists Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
